Single-Use Bioprocess Equipment

In many biopharmaceutical processes, single-use, disposable products have become a viable alternative to traditional stainless steel process systems. They offer several advantages:

  • Speed to Market: There are many single use process systems such as disposable mixing and bioreactor systems that are “off the shelf” items.
  • Lower Capital Costs: The use of disposable bioprocess equipment eliminates costly CIP and SIP equipment as well as all of the associated fixed piping systems.
  • Lower Utilities: Single-Use systems eliminate the expense of costly items such as cleaning chemicals and steam. Using disposables also greatly reduces energy costs and water use.
  • Safety: As single-use bioprocess equipment requires much less product transfer from vessel to vessel, workers do not come in contact with cytotoxic drugs.
  • Reduced Risk of Cross Contamination: Cleaning deficiencies are a common regulatory issue, which is eliminated using disposable setups and equipment.
  • Smaller Clean Room Requirements: This also reduces capital and operating expenditures.
  • Validation: Costly cleaning validation protocols and associated paperwork are eliminated.
Single Use Resource Center

We have published a series of articles on our Blog, Hollandaptblog.com addressing single use products, their technical features and application data. Listed below are links to the various posts. We will continue to update these as more are published.

Holland offers an extensive line of single-use bioporcess products. We bring the same level of process expertise, product knowledge and commitment to quality in our disposables program as we have in our sanitary process equipment business for the past 50 years. . We offer a broad range of single-use products, ranging from turnkey bioreactors and mixing systems to single-use manifolds, disposable sampling assemblies, plastic fittings, valves, tubing and clamps.

We can offer custom solutions designed to improve production efficiency, reduce contamination risks, increase speed to market and minimize cleaning validation, keeping your company focused on producing high quality products.


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