Pure-Fit SIB Fittings

Pure-Fit SIB Manifolds

Pure-Fit SIB is a smooth inner bore (SIB) fitting and assembly system that provides a seamless transition of tubing and fittings, maintaining complete fluid integrity throughout the system. Quick and secure connections, as well as the prevention of fluid contamination and product loss through leakage, are critical in biopharmaceutical applications. Pure-Fit SIB, with its patented 360° compression seal, is the solution to these potential problems.

Pure-Fit SIB’s unique internal design reduces the risk of tubing being punctured or cut from sharp, barbed edges like those on traditional fitting systems. Because of the smooth inner bore design, Pure-Fit SIB eliminates turbulence (dead space) or stagnation of fluid flow, which creates areas for potential bacteria growth.

The Pure-Fit SIB system is ideal for making single-use manifolds and tubing sets. It offers more flexibility than molded manifolds. Pure-Fit SIB fittings systems are compatible with all of our silicone tube offerings as well as TPE tube including C-Flex. Manifolds can be assembled in-house. Holland Applied Technologies also offers manifold assembly services, including clean room assembly and gamma irradiation.

Pure-Fit SIB Characteristics

Pure-Fit SIB utilizes the patented BarbLock® retention and sealing system, providing complete 360° compression along the entire fitting system. Constructed from the highest quality polypropylene or PVDF, the components and systems are completely autoclavable and sterilizable. Pure-Fit SIB fitting systems have been engineered to provide a complete, undisturbed fluid flow path through all flexible tubing. Saint-Gobain Performance Plastics offers a broad line of flexible tubing formulations that are ideally suited for use in conjunction with your particular application and the Pure-Fit® SIB® system.


Pure-Fit SIB fitting systems meet all USP Class VI criteria and have been physically tested to meet the most demanding applications

Features/Benefits of Pure-Fit SIB

  • Total smooth inner bore (SIB)
  • Eliminates entrapment and leak points that occur with traditional fitting systems
  • Complete 360° compression along the entire fitting system
  • No excessive voids at the interface or in the fluid path
  • Utilizes the patented BarbLock® retention and seal system
  • Compatible with all flexible tubing
  • Complete customized manifold and assembly systems
  • Fully autoclavable and sterilizable
  • Now available in animal-free polypropylene construction
Pure-Fit SIB Typical Physical Properties

Property Polypropylene PVDF
Tensile Strength,psi (MPa) ASTM D638-91 4,800 (33.1) 6,300 (43.4)
Flexural Modulus,psi (MPa) ASTM D790-92 145,000 (999.7) 290,000 (1,999.5)
Hardness (Shore D)ASTM D2240-91 7278
Heat Deflection ASTM D648-82 ºF (ºC) @66 psiºF (ºC) @264 psi 189 (87)— 266 (130) 221 (105)
Water Absorption (%)ASTM D570-81 0.010.03
Max. Recommended Working Temp., ºF (ºC) 200 (93) 275 (135)

Pure-Fit SIB Typical Applications

  • Sterile filling & aseptic fluid transfer
  • Biopharmaceutical manufacturing
  • Filtration & fermentation
  • Peristaltic pump sets
  • Cell harvest & media process systems
  • Bioreactor process lines

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